Cathepsin L/Tetrain

BLASTp Hit to Protein of Known or Suspected Function:
Organism: Tetrahymena pyriformis
GI Number: 3273233
E-value: 2e-133

Protein and Coding Sequences:

TGD ID Number: 125.m00080

Evidence: TIGR Preliminary Gene Prediction 08/2004: predicted gene structure is fully supported by ESTs.

Coding Sequence:

ATGAAATTAACTTATTTCCTTGTTGGCTTAGCTTTAATCGGTGCTGCCACTGTTTACTTA
ATTACAAGAAACCCCAACGGTGATGGTCATCTTGATATGTATTCATTCTTAAAATTCAAG
AGATCTTTCAATGTTTAATATCACAATGAATCTGAGGAATCTTACAGACTTTCTGTCTTC
TTAGAAAACTTAAAGATGATTGAAAAGCACAATGCTGATTCAACTAGAACCTATGACCAA
GAAGTCAACTAATTCGCTGATTTAACTATTGAAGAATTCGAATCTAGATATCTTATGAAG
TCTCTTCCTTCCTAATTAAACAAGAACCTCGCCGTCTTAAACTTAAATGAGACTGCTAGT
CAACCTATCGACTGGACTACTAAGAATGTTTTACCCGGTGTTAAAAACTAATAATAATGC
GGTTCCTGCTGGGCTTTCTCTACTGCTGGTTTACTTGAATCTGTTTACAACATCCACAAC
AAACCTAATACTCCTATTTCTTTCTCTGAATAATAGCTTGTTGATTGCTGTGGTGCTGAA
GGTTTCGGATGTGAAGGTTGTGGTGGTGCCTGGCCTACTGATGCTGTTGCCTACACTTAA
AAATTCGGTATTGTCTAAGAGAGTTAATATGCTTACACTGCTAAGGATGGCAAATGCAAC
AAAACTCTTGAAGGTGTTGGTTACAAGCCTTCTTAATAATTCTAAGTTACTGCTAGTGAT
GCTGCCCTTCAAGCCGCTCTCTAGAATTAACCTATCTCTATCTGCGTTGATGCCTCCTAA
TGGTCTTCTTATGCTTCGGGTGTTTTCCCTTAAAGCAAGTGCAGTTCTGATCCCAACGCA
GCTGATCATGCTGTTTTACTTGTTGGTTACAATGCTAATGGTACTTGGAAGGTTAGAAAC
TCTTGGGGTACTTCTTGGGGTGTAGGTGGTTACATCACACTTGCTGCTGGTAATACTTGC
GGTCTTGAAAACTATGCAATTTATGCCACATATTGA

Protein Sequence:

MKLTYFLVGLALIGAATVYLITRNPNGDGHLDMYSFLKFKRSFNVQYHNESEESYRLSVF
LENLKMIEKHNADSTRTYDQEVNQFADLTIEEFESRYLMKSLPSQLNKNLAVLNLNETAS
QPIDWTTKNVLPGVKNQQQCGSCWAFSTAGLLESVYNIHNKPNTPISFSEQQLVDCCGAE
GFGCEGCGGAWPTDAVAYTQKFGIVQESQYAYTAKDGKCNKTLEGVGYKPSQQFQVTASD
AALQAALQNQPISICVDASQWSSYASGVFPQSKCSSDPNAADHAVLLVGYNANGTWKVRN
SWGTSWGVGGYITLAAGNTCGLENYAIYATY*

Peptides Identified in Mass Spectrometry Analysis: 4
LSVFLENLK
SFNVQYHNESEESYR
FGIVQESQYAYTAK
TYDQEVNQFADLTIEEFESR

Number of Independent Analyses from which Peptide Data was Obtained: 3

Relevant Tetrahymena References:

 

Presence in Phagosome Proteomes of Other Organisms:

Mus musculus (Garin, J., et al. 2001. The Phagosome Proteome: Insight Into Phagosome Functions. J Cell Biol. 152:165-180.)

Entamoeba histolytica (Okada, M., et al. 2005. Proteomic Analysis of Phagocytosis in the Enteric Protozoan Parasite Entamoeba histolytica. Euk Cell. 4:827-831.)

GO database